| Customization: | Available |
|---|---|
| Application: | Internal Medicine |
| Usage Mode: | IV |
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| Product name | Metamizole Sodium Injection |
| Product Type | Antipyretic and analgesic for Human |
| Route of Administration | Intramuscularly, intravenously |
| 1. Dosage: | 500mg 2ml,500mg5ml 2.5g5ml |
| 2. Quality standard | CP |
| 3. Packaging: | 10amps/box, 100amps/box |
| 4. Storage | Store below 25ºC Protect from light |
| 5. Period of validity | 3 years |
Metamizole Sodium injection analgin injection dipyrone injection for human 500mg/2ml
Description:A clear, colourless or slightly yellow liquid, is a sterile solution of metamizole sodium in Water for injection
Composition:
Each 5ml ampoule contains: Metamizole Sodium 500mg.
Indications:
Metamizole sodium injection is used in cases of acute and severe pain after operations and traumas, pain associatewith neoplastic diseases, colicky pain etc.
contraindications:
Hypersensitivity to metamizole and other pyrazolone derivatives, acute hepatic porphyria, inborn glucose-6-phophate dehydrogenase deficiency, severe renal or hepatic diseases, blood diseases (such as aplastic anemia, leucopenand agranulocytosis), pregnancy (the first and the last trimester),. Parenteral administration of Metamizole sodiumcontraindicated in under 1 year-old children.
Warnings and Precautions:
Metamizole sodium is used with increased caution in patients with a history for hypersensitivity to foods and drug(particularly to analgesic and nonsteroidal anti-inflammatory agents) and also in patients suffering from bronchiasthma.Ouincke's edema.chronic pulmonary infections.In patients with hypotension and unstable blood pressurMetamizole sodium should not be used parenterally, If Metamizole sodium application is quite necessary, the blocpressure and the heart rate should be monitored. In cases of prolonged Metamizole sodium treatment, regular bloccount checks are necessary (differential count of the white blood cells). The high Metamizole sodium doses cainfluence unfavorably the active attention, Because of this in these cases driving and working with machines are not advised.
Metamizole sodium injection should not be used in pregnancy and lactation.
Adverse Reactions:After prolonged administration very rarely can be observed agranulocytosis, leucopenia and thrombocytopeniproteinuria, interstitial nephritis. In sensitive patients rashes, urticaria, Quincke's edema, asthmatic attacks, and verarely anaphylactic shock are possible.
Drug Interactions:
Metamizole Sodium potentiates the analgesic and antipyretic action of the nonsteroidal anti-inflammatory drugs. ThMetamizole Sodium effects are potentiated by the tricyclic antidepressants, oral contraceptive agents, allopurinoalcohol. Metamizole Sodium decreases the activity of the coumarin anticoagulants and plasma levels of cyclosporiThe enzyme inductors (barbiturates, phenylbutazone) attenuate the etamizole Sodium efiectMetamizole Sodium potentiates the effects of the drugs possessing CNS depressant activity, Concurrent administrtion with chlorpromazine is related with a risk of severe hypothermia. Metamizole Sodium can be used in combinatiowith buscolysin. atropin.
Posology:
Ampoules: The ampoules can be administered intramuscularly, The single dose in all age groups is 8 to l6 mg/kg bocweight. The dose should be given according to the following scheme: 16 to 31 kg body weight - 250 mg Metamizolsodium; 32 to 46 kg body weight - 500 mg Metamizole sodium; 47 - 62 kg body weight - 500 - 750 mg Metamizosodium; and over 63 kg body weight - 750 - 1000 mg Metamizole sodium. In cases of persistent pain, the dose can trepeated after 6 to 8 hours. Maximum daily dose - 4.0 g Metamizole sodium. Metamizole sodium should not be useparenterally for a period longer than 3 days.Storage: Store in a cool and dry place, protect from light.
Shelf Life: 36 months.
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