Artemether Injection (Anti-malaria) 1ml 20mg 40mg 80mg

• Customization: Available
• Application: Internal Medicine
• Usage Mode: Injection
• Model NO.: 20mg40mg80mg1ml
• State: Liquid
• Shape: Injection
• Type: Organic Chemicals
• Pharmaceutical Technology: Chemical Synthesis
• Drug Reg./Approval No.: SL2022001
• Drug Ad Approval No.: SL2022001
• Drug Class: Antimalarial
• Form of Business: Manufacturing Enterprise
• Register Dossier: Available
• COA: Available
• Test Repot: Available
• Authentication: GMP
• Qualification Certificate: Complete
• Transport Package: Carton
• Specification: 1ml 20mg40mg80mg
• Trademark: shenglu or OEM
• Origin: Shandong China
• HS Code: 3001909099
• Production Capacity: 1 Billion/Year

Product Description

Product Description

Product name	Artemether injection
Product Type	Antimalarial drugs for human use
Route of Administration	Intramuscularly
1. Dosage:	20mg,40mg,80mg 1ml
2. Quality standard	Company standard
3. Packaging:	5amps/box
4. Storage	below 25ºC Airtight Storage
5. Period of validity	3 years

ARTEMETHER INJECTION

NOMENCLATURE:
The drug is mainly composed of Artemether. The chemical name is (3R, 5aS, 6R, 8aS, 9R, 10S, 12R, 12aR)-decahydro-10-methoxy-3,6,9-trimethy1-3,12-epoxy-12H-pyrano[4,3-j]-1,2-ben-zodioxepin

CHARACTER:
A colorless or yellowish clear oily solution.

PHARMACOLOGY AND TOXICOLOGY:

Animal pharmacodynamics showed that the drug isa strong schizonticide. Parasitemia clearance occurs rapidly with stable efficacy after administration. It is also effective against chloroquine-resistant P. falciparum malaria. Acute toxicity studies on animals showed that the LD50 of Artemether in mice of a single i.g. administration is 895mg/kg and a single i.m. injection is 296mg/kg; in rats, the LD50 of a single i.m. injection is 597mg/kg. This proves the toxicity of Artemether is quite low.

PHARMACOKINETICS:

The drug is absorbed rapidly and completely after i.m. injection. The maximum blood concentration of the drug is observed in about 7 hours after i.m. injection of 10mg/kg in human body. The peak value is about 0.8ug/ml with the plasma half-life of about 13 hours. It is widely distributed in the body with the highest level found in the brain and followed by the liver and kidney. It is mainly excreted in the feces with a part in urine.

INDICATIONS:

Antimalarial drug. For the treatment of all kinds of malaria including the chloroquine-resistant P. falciparum malaria and the first aid of critical malaria.

USAGE AND DOSAGE:

The drug is used for intramuscular injection, five days course with the initial dose of 3.2mg/kg, followed by 1.6mg/kg for the following 4 days.
The initial dose for adults is 160mg, followed by 80mg every time from the 2^nd to 5nd day. The dose for children or overweight patients should be decreased or increased on the basis of the individual weight or under the doctor's prescription.

ADVERSE REACTIONS:

Clinical dosage exhibits slight adverse reactions. A transient low fever and reticulocytopenia may occur individual cases. Slight rise of SGOT and SGPT may occur in individual cases. Arrhythmia may occur in rare cases (such as ventricular tachycardia).

CONTRAINDICATIONS:

Hypersensibility to any one of constituents.

PRECAUTIONS:

In case of freeze due to coldness, please warm it before use.

PREGNANCY AND LACTATION:

It should be used with caution in the first trimester of pregnancy since some fetus absorption has been observed.

ADMINISTRATION FORCHILDREN:

For children, the dose should be chosen as follows:

The dose for children should be decreased or increased on the basis of individual weight or under the doctor's prescription.

DRUG INTERACTIONS:

Studies and reviews in the literature demonstrated that the active substance of Artemether had no interactions with other drugs on decreasing therapeutic effects and increasing toxicity and side effects in human bodies

OVERDOSE:

Although no case of overdosage has been documented, in case of accident, symptomatic treatment is recommended under the instruction of doctors.

PRESENTATION:

Solution for injection, ampoule of 20mg, 40mg, 80mg/1ml, box of 6 VALIDITY: 3years.

STORAGE:

Store in well closed container, protected from light and stored in a cool place.
 

Detailed Photos

 

Company Profile

Our company are looking for dealers or agents all over the world.
lf you are interested in our products, please contact us immediately.
Looking forward to cooperating with you!

Shandong Shenglu Pharmaceutical Co., Ltd. is a professional pharmaceutical preparation manufacturer in China and a professional supplier of pharmaceutical preparations. For more than 20 years, we have been focusing on the production and sales of Western medicine preparation,Products are exported to Asia, Africa, the Middle East, South America and many other countries, such as Cambodia, Philippines, Vietnam, Afghanistan, Pakistan, Nigeria, Congo, Benin, Guinea, Turkmenistan, Gambia and so on.
To supply sustainable, high quality products, competitive price and satisfactory service is our mission. We won high recognition in the international market by professional product knowledge, efficient supply chain management and excellent service, establishing extensive and mature distribution channels in international market.
Professionalism, honesty and trustworthiness are our cultures. We will try our best to offer good quality products with competitive prices and fast delivery for our customers. We are looking forward to setting up long-term cooperation relationship with you.