| Customization: | Available |
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| Application: | Treat Severe Diabetic Gastroparesis |
| Usage Mode: | Injection |
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Metoclopramide increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines.
Metoclopramide oral (taken by mouth) is used for 4 to 12 weeks to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief.
| Generic name: | metoclopramide (oral/injection) |
| Brand names: | Metozolv ODT, Reglan |
| Parenteral: | injectable solution (10 mg/mL; 10 mg/mL preservative-free; 4 mg/mL), intravenous solution (6 mg/25 mL-NaCl 0.9%) |
| Oral: | 10 mg 4 times daily, 30 minutes before meals and at bedtime, for 2 to 8 weeks depending on clinical response. |
| Drug class: | GI stimulants, Miscellaneous antiemetics |
MetoclopramideInjection is a clear, colourless solution in a plastic ampoule. Metoclopramide Injection 10 mg in 2 mL is available in packs of 10 or 50 ampoules (AUST R 11364) * Not all pack sizes may be marketed.
Usual Adult Dose for Nausea/Vomiting:
Postoperative nausea and vomiting:
Parenteral: 10 to 20 mg IM at or near the end of surgery
Usual Adult Dose for Gastroesophageal Reflux Disease:
Oral: 10 to 15 mg up to 4 times a day 30 minutes before meals and at bedtime, depending upon symptoms being treated and clinical response. Therapy should not exceed 12 weeks.
Usual Adult Dose for Small Intestine Intubation:
If the tube has not passed the pylorus with conventional methods in 10 minutes, a single (undiluted) dose may be administered IV slowly over 1 to 2 minutes:
Adults and pediatric patients greater than or equal to 14 years: 10 mg IV as a single dose administered over 1 to 2 minutes.
Usual Adult Dose for Radiographic Exam:
Adults and pediatric patients greater than or equal to 14 years: 10 mg IV as a single dose administered over 1 to 2 minutes to facilitate gastric emptying where delayed gastric emptying interferes with radiological examination of the stomach and/or small intestine.
Usual Adult Dose for Gastroparesis:
During the earliest manifestations of diabetic gastric stasis, oral administration may be initiated. If severe symptoms are present, therapy should begin with IM or IV administration for up to 10 days until symptoms subside at which time the patient can be switched to oral therapy. Since diabetic gastric stasis is often recurrent, therapy should be reinstituted at the earliest manifestation.
Parenteral: 10 mg 4 times daily, IV (slowly over a 1 to 2 minute period) or IM for up to 10 days.
Oral: 10 mg 4 times daily, 30 minutes before meals and at bedtime, for 2 to 8 weeks depending on clinical response.
Store tightly away from light.
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