Paracetamol Injection750mg/ 5ml Producing Paracetamol Injection Manufacturer/Factory

• Customization: Available
• Application: All
• Usage Mode: Injection
• Model NO.: Paracetamol Injection
• State: Liquid
• Shape: Oral Liquid
• Type: Biological Products
• Pharmaceutical Technology: Chemical Synthesis
• Period of Validity: 24 Monthes
• Transport Package: Box
• Specification: 100ml/300ml/750ml
• Trademark: UK
• Origin: UK
• HS Code: 3001909099
• Production Capacity: 5000000000000000000000PC/Year

Product Description

Paracetamol Injection750mg/  5ml producing Paracetamol Injection manufacturer/factory
This product is acetanilide antipyretic analgesic. By inhibiting cyclooxygenase, selective inhibition of prostaglandin synthesis in hypothalamic thermoregulatory center leads to peripheral vascular dilation and sweating, thus achieving antipyretic effect, which is similar to aspirin. It plays an analgesic role by inhibiting the synthesis and release of prostaglandins, etc. and raising the pain threshold. It is a peripheral analgesic drug with a weaker effect than aspirin and is only effective for light and moderate pain. This product has no obvious anti-inflammatory effect.

Pharmacokinetics :

It is absorbed rapidly and completely from the gastrointestinal tract after oral administration (absorption may be reduced by taking the drug after a high-carbohydrate diet), and is evenly distributed in body fluids after absorption, with about 25% binding to plasma proteins. In small doses (blood concentration <60μg/ml), protein binding was not obvious, and in large or toxic doses, the binding rate was higher, up to 43%. 90-95% of the product is metabolized in the liver, and mainly binds to glucuronic acid, sulfuric acid and cysteine. Intermediate metabolites have toxic effects on the liver. The half-life β is generally 1 to 4 hours (average 2 hours), and the kidney function is unchanged when it is incomplete, but it may be prolonged in some liver diseases, the elderly and newborns can be prolonged, and children are shortened. The blood concentration can reach the peak 0.5~2 hours after oral administration, and the blood concentration is 5~20μg/ml when the dose is below 650mg, and the duration of action is 3~4 hours. During lactation, women took 650mg of the product, and reported the milk concentration of 10-15 μg/ml in 1 to 2 hours; The half-life β is 1.35 to 3.5 hours. The product is excreted from the kidneys mainly in the form of binding with glucuronic acid, and about 3% is excreted in urine in its original form within 24 hours.